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NHLH1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q02575 |
|---|---|
| Clone Names | 100406142 |
| Gene ID | 4807 |
|---|---|
| Other Names | Helix-loop-helix protein 1, HEN-1, Class A basic helix-loop-helix protein 35, bHLHa35, Nescient helix loop helix 1, NSCL-1, NHLH1, BHLHA35, HEN1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NHLH1 |
|---|---|
| Synonyms | BHLHA35, HEN1 |
| Function | May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The helix-loop-helix (HLH) proteins are a family ofputative transcription factors, some of which have been shown toplay an important role in growth and development of a wide varietyof tissues and species. Four members of this family have beenclearly implicated in tumorigenesis via their involvement inchromosomal translocations in lymphoid tumors: MYC (MIM 190080),LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[suppliedby OMIM].
References
Manetopoulos, C., et al. Biochem. Biophys. Res. Commun. 307(4):891-899(2003)Bao, J., et al. Development 127(2):425-435(2000)Lipkowitz, S., et al. J. Biol. Chem. 267(29):21065-21071(1992)Brown, L., et al. Proc. Natl. Acad. Sci. U.S.A. 89(18):8492-8496(1992)Begley, C.G., et al. Proc. Natl. Acad. Sci. U.S.A. 89(1):38-42(1992)
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