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PSG2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P11465
Clone Names 100603088
Additional Information
Gene ID 5670
Other Names Pregnancy-specific beta-1-glycoprotein 2, PS-beta-G-2, PSBG-2, Pregnancy-specific glycoprotein 2, Pregnancy-specific beta-1 glycoprotein E, PS-beta-E, PSG2, PSBG2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSG2
Synonyms PSBG2
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

The human pregnancy-specific glycoproteins (PSGs) are afamily of proteins that are synthesized in large amounts byplacental trophoblasts and released into the maternal circulationduring pregnancy. Molecular cloning and analysis of several PSGgenes has indicated that the PSGs form a subgroup of thecarcinoembryonic antigen (CEA) gene family, which belongs to theimmunoglobulin superfamily of genes. Members of the CEA familyconsist of a single N domain, with structural similarity to theimmunoglobulin variable domains, followed by a variable number ofimmunoglobulin constant-like A and/or B domains. Most PSGs have anarg-gly-asp (RGD) motif, which has been shown to function as anadhesion recognition signal for several integrins, in theN-terminal domain (summary by Teglund et al., 1994 [PubMed7851896]). For additional general information about the PSG genefamily, see PSG1 (MIM 176390).

References

Tsavaris, N., et al. J Chemother 21(6):673-680(2009)Mennuni, C., et al. Int. J. Cancer 117(3):444-455(2005)Colland, F., et al. Genome Res. 14(7):1324-1332(2004)Grimwood, J., et al. Nature 428(6982):529-535(2004)Teglund, S., et al. Genomics 23(3):669-684(1994)

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$ 277.78
Cat# BP16905b
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