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POLS Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q5XG87
Clone Names 100603183
Peptide ID 100603183
Additional Information
Gene ID 11044
Other Names Non-canonical poly(A) RNA polymerase PAPD7, DNA polymerase sigma, LAK-1, PAP-associated domain-containing protein 7, TRAMP-like complex polyadenylate polymerase, Terminal uridylyltransferase 5, TUTase 5, Topoisomerase-related function protein 4-1, TRF4-1, PAPD7, POLS, TRF4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAPD7
Synonyms POLS, TRF4
Function Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post- transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.
Cellular Location Cytoplasm. Nucleus, nucleoplasm. Note=Excluded from nucleolus, weak staining detected in the cytoplasm
Research Areas
Citations (0)

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The protein encoded by this gene is a DNA polymerase thatis likely involved in DNA repair. In addition, the encoded proteinmay be required for sister chromatid adhesion. Alternativelyspliced transcript variants that encode different isoforms havebeen described.


Jarjanazi, H., et al. Hum. Mutat. 29(4):461-467(2008)Carson, D.R., et al. Proc. Natl. Acad. Sci. U.S.A. 98(15):8270-8275(2001)Wang, Z., et al. Science 289(5480):774-779(2000)Walowsky, C., et al. J. Biol. Chem. 274(11):7302-7308(1999)

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$ 80.00
Cat# BP16915c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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