TPRX1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8N7U7 |
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Clone Names | 100422183 |
Gene ID | 284355 |
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Other Names | Tetra-peptide repeat homeobox protein 1, TPRX1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | TPRX1 {ECO:0000303|PubMed:36074823, ECO:0000312|HGNC:HGNC:32174} |
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Function | Transcription factor expressed after fertilization required for zygotic genome activation (ZGA), a critical event in early embryonic development during which the developmental control passes from maternally provided mRNAs to the expression of the zygotic genome after fertilization (PubMed:35314832, PubMed:36074823). Binds and activates expression of key ZGA marker genes, such as NANOGNB, ZSCAN4, DUXB, KLF5 and DPPA3 (PubMed:36074823). Binds to regulatory DNA sequences containing a 5'-TAATCC-3' sequence motif (PubMed:36074823). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Homeobox genes encode DNA-binding proteins, many of whichare thought to be involved in early embryonic development. Homeoboxgenes encode a DNA-binding domain of 60 to 63 amino acids referredto as the homeodomain. This gene is a member of the TPRX homeoboxgene family.
References
Booth, H.A., et al. Gene 387 (1-2), 7-14 (2007) :
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