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SIGLEC9 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y336 |
|---|---|
| Clone Names | 100617115 |
| Gene ID | 27180 |
|---|---|
| Other Names | Sialic acid-binding Ig-like lectin 9, Siglec-9, CDw329, Protein FOAP-9, CD329, SIGLEC9 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SIGLEC9 |
|---|---|
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Location | Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). Found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary, adrenal gland, colon, trachea, cerebellum, testis, small intestine and spinal cordon |
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Provided below are standard protocols that you may find useful for product applications.
Background
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
References
Belisle, J.A., et al. Mol. Cancer 9, 118 (2010) :von Gunten, S., et al. Shock 32(4):386-392(2009)Rashmi, R., et al. Pediatr. Res. 66(3):266-271(2009)Carlin, A.F., et al. Blood 113(14):3333-3336(2009)Avril, T., et al. J. Immunol. 173(11):6841-6849(2004)
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