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PTPN18 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99952
Clone Names 100617184
Peptide ID 100617184
Additional Information
Gene ID 26469
Other Names Tyrosine-protein phosphatase non-receptor type 18, Brain-derived phosphatase, PTPN18, BDP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTPN18
Synonyms BDP1
Function Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
Cellular Location Nucleus. Cytoplasm
Tissue Location Expressed in brain, colon and several tumor- derived cell lines.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, the mitotic cycle, andoncogenic transformation. This PTP contains a PEST motif, whichoften serves as a protein-protein interaction domain, and may berelated to protein intracellular half-live. This protein candifferentially dephosphorylate autophosphorylated tyrosine kinasesthat are overexpressed in tumor tissues, and it appears to regulateHER2, a member of the epidermal growth factor receptor family ofreceptor tyrosine kinases. Two transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].


Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)Blanchetot, C., et al. Methods 35(1):44-53(2005)Gandhi, T.K., et al. DNA Res. 12(2):79-89(2005)

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$ 80.00
Cat# BP16925b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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