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SLC19A2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O60779
Clone Names 100623120
Additional Information
Gene ID 10560
Other Names Thiamine transporter 1, ThTr-1, ThTr1, Solute carrier family 19 member 2, Thiamine carrier 1, TC1, SLC19A2, THT1, TRMA
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC19A2
Synonyms THT1, TRMA
Function High-affinity transporter for the intake of thiamine (PubMed:10542220, PubMed:10391222, PubMed:33008889, PubMed:35512554, PubMed:35724964). Mediates H(+)-dependent pyridoxine transport (PubMed:33008889, PubMed:35512554, PubMed:35724964).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung.
Research Areas
Citations (0)
citation

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Background

This gene encodes the thiamin transporter protein.Mutations in this gene cause thiamin-responsive megaloblasticanemia syndrome (TRMA), which is an autosomal recessive disordercharacterized by diabetes mellitus, megaloblastic anemia andsensorineural deafness.

References

Bailey, S.D., et al. Diabetes Care (2010) In press :Bergmann, A.K., et al. Pediatr Blood Cancer 54(2):273-278(2010)Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Mee, L., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (1), G197-G206 (2009) :

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$ 277.78
Cat# BP16928c
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