|Other Names||Thiamine transporter 1, ThTr-1, ThTr1, Solute carrier family 19 member 2, Thiamine carrier 1, TC1, SLC19A2, THT1, TRMA|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||High-affinity transporter for the intake of thiamine.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes the thiamin transporter protein.Mutations in this gene cause thiamin-responsive megaloblasticanemia syndrome (TRMA), which is an autosomal recessive disordercharacterized by diabetes mellitus, megaloblastic anemia andsensorineural deafness.
Bailey, S.D., et al. Diabetes Care (2010) In press :Bergmann, A.K., et al. Pediatr Blood Cancer 54(2):273-278(2010)Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Mee, L., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (1), G197-G206 (2009) :
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