CGNL1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q0VF96 |
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Clone Names | 110712006 |
Gene ID | 84952 |
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Other Names | Cingulin-like protein 1, Junction-associated coiled-coil protein, Paracingulin, CGNL1, JACOP, KIAA1749 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CGNL1 |
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Synonyms | JACOP, KIAA1749 |
Function | May be involved in anchoring the apical junctional complex, especially tight junctions, to actin-based cytoskeletons. |
Cellular Location | Cell junction, tight junction {ECO:0000250|UniProtKB:Q6AW69}. Note=Localizes to the apical junction complex composed of tight and adherens junctions (PubMed:22891260). In the liver and kidney, it is also found along non-junctional actin filament bundles in addition to the apical junction (By similarity) {ECO:0000250|UniProtKB:Q6AW69, ECO:0000269|PubMed:22891260} |
Tissue Location | Smooth muscle, spleen, testis, fetal brain, amygdala, corpus callosum, cerebellum, thalamus and subthalamic nucleus of adult brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CGNL1 may be involved in anchoring the apical junctional complex, especially tight junctions, to actin-based cytoskeletons (By similarity).
References
Guillemot, L., et al. Mol. Biol. Cell 19(10):4442-4453(2008)Ohnishi, H., et al. J. Biol. Chem. 279(44):46014-46022(2004)Shozu, M., et al. N. Engl. J. Med. 348(19):1855-1865(2003)
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