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ARAP2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8WZ64
Clone Names 110717009
Peptide ID 110717009
Additional Information
Gene ID 116984
Other Names Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, Centaurin-delta-1, Cnt-d1, Protein PARX, ARAP2, CENTD1, KIAA0580
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARAP2
Synonyms CENTD1, KIAA0580
Function Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity).
Cellular Location Cytoplasm.
Tissue Location Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes
Research Areas
Citations (0)

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The protein encoded by this gene contains ARF-GAP,RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homologydomains. The protein is a phosphatidylinositol(3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, butit lacks the predicted catalytic arginine in the RHO-GAP domain anddoes not have RHO-GAP activity. The protein associates with focaladhesions and functions downstream of RhoA to regulate focaladhesion dynamics.


Gavicherla, B., et al. Infect. Immun. 78(11):4532-4541(2010)Liu, C., et al. Mol. Med. 14 (9-10), 575-581 (2008) :Yoon, H.Y., et al. J. Cell. Sci. 119 (PT 22), 4650-4666 (2006) :Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP16947a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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