|Other Names||Thrombospondin-2, THBS2, TSP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.|
|Tissue Location||High expression in invertebral disk tissue.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to thethrombospondin family. It is a disulfide-linked homotrimericglycoprotein that mediates cell-to-cell and cell-to-matrixinteractions. This protein has been shown to function as a potentinhibitor of tumor growth and angiogenesis. Studies of the mousecounterpart suggest that this protein may modulate the cell surfaceproperties of mesenchymal cells and be involved in cell adhesionand migration.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)Meng, H., et al. J. Biol. Chem. 285(30):23047-23055(2010)Shaffer, J.R., et al. Nutr Metab Cardiovasc Dis (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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