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MTIF2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P46199
Clone Names 100405120
Peptide ID 100405120
Additional Information
Gene ID 4528
Other Names Translation initiation factor IF-2, mitochondrial, IF-2(Mt), IF-2Mt, IF2(mt), MTIF2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTIF2
Function One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Cellular Location Mitochondrion.
Tissue Location Expressed in all tissues examined. Highest level in skeletal muscle
Research Areas
Citations (0)

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During the initiation of protein biosynthesis, initiationfactor-2 (IF-2) promotes the binding of the initiator tRNA to thesmall subunit of the ribosome in a GTP-dependent manner.Prokaryotic IF-2 is a single polypeptide, while eukaryoticcytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine livermitochondria contain IF-2(mt), an 85-kD monomeric protein that isequivalent to prokaryotic IF-2. The predicted 727-amino acid humanprotein contains a 29-amino acid presequence. Human IF-2(mt) shares32 to 38% amino acid sequence identity with yeast IF-2(mt) andseveral prokaryotic IF-2s, with the greatest degree of conservationin the G domains of the proteins. Two transcript variants encodingthe same protein have been found for this gene. [provided byRefSeq].


Dick, D.M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2010) In press :Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)Miura, E., et al. Plant Cell 19(4):1313-1328(2007)Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004)Overman, R.G. Jr., et al. Biochim. Biophys. Acta 1628(3):195-205(2003)

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$ 80.00
Cat# BP16956a
Availability: In Stock
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