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WNT9B Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O14905
Clone Names 100406006
Additional Information
Gene ID 7484
Other Names Protein Wnt-9b, Protein Wnt-14b, Protein Wnt-15, WNT9B, WNT14B, WNT15
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WNT9B
Synonyms WNT14B {ECO:0000303|PubMed:11604992}, WN
Function Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal embryonic kidney development, and for normal development of the urogenital tract, including uterus and part of the oviduct and the upper vagina in females, and epididymis and vas deferens in males. Activates a signaling cascade in the metanephric mesenchyme that induces tubulogenesis. Acts upstream of WNT4 in the signaling pathways that mediate development of kidney tubules and the Muellerian ducts. Plays a role in cranofacial development and is required for normal fusion of the palate during embryonic development (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix. Secreted
Tissue Location Moderately expressed in fetal kidney and adult kidney. Also found in brain
Research Areas
Citations (0)
citation

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Background

The WNT gene family consists of structurally related genesthat encode secreted signaling proteins. These proteins have beenimplicated in oncogenesis and in several developmental processes,including regulation of cell fate and patterning duringembryogenesis. This gene is a member of the WNT gene family. Studyof its expression in the teratocarcinoma cell line NT2 suggeststhat it may be implicated in the early process of neuronaldifferentiation of NT2 cells induced by retinoic acid. This gene isclustered with WNT3, another family member, in the chromosome 17q21region.

References

Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Ravel, C., et al. Fertil. Steril. 91 (4 SUPPL), 1604-1607 (2009) :Chiquet, B.T., et al. Hum. Mol. Genet. 17(14):2212-2218(2008)

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$ 277.78
Cat# BP16959c
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