|Other Names||Vacuolar protein sorting-associated protein 37A, hVps37A, ESCRT-I complex subunit VPS37A, Hepatocellular carcinoma-related protein 1, VPS37A, HCRP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.|
|Cellular Location||Late endosome membrane; Peripheral membrane protein. Nucleus|
|Tissue Location||Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas.|
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Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Lamesch, P., et al. Genomics 89(3):307-315(2007)Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) :Eastman, S.W., et al. J. Biol. Chem. 280(1):628-636(2005)Bache, K.G., et al. Mol. Biol. Cell 15(9):4337-4346(2004)Stuchell, M.D., et al. J. Biol. Chem. 279(34):36059-36071(2004)
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