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GUCY2F Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P51841
Clone Names 100406150
Peptide ID 100406150
Additional Information
Gene ID 2986
Other Names Retinal guanylyl cyclase 2, RETGC-2, Guanylate cyclase 2F, retinal, Guanylate cyclase F, GC-F, Rod outer segment membrane guanylate cyclase 2, ROS-GC2, GUCY2F, GUC2F, RETGC2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GUCY2F
Synonyms GUC2F, RETGC2
Function Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Retina. Localized exclusively in the outer nuclear layer and inner segments of the rod and cone photoreceptor cells
Research Areas
Citations (0)

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Background

The protein encoded by this gene is a guanylyl cyclasefound predominantly in photoreceptors in the retina. The encodedprotein is thought to be involved in resynthesis of cGMP afterlight activation of the visual signal transduction cascade,allowing a return to the dark state. This protein is a single-passtype I membrane protein. Defects in this gene may be a cause ofX-linked retinitis pigmentosa.

References

Blackford, A., et al. Cancer Res. 69(8):3681-3688(2009)Helten, A., et al. J. Neurochem. 103(4):1439-1446(2007)Wood, L.D., et al. Hum. Mutat. 27(10):1060-1061(2006)Ross, M.T., et al. Nature 434(7031):325-337(2005)Laura, R.P., et al. Biochemistry 37(32):11264-11271(1998)

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$ 80.00
Cat# BP16965b
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