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KRT6A Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P02538
Clone Names 100427176
Peptide ID 100427176
Additional Information
Gene ID 3853
Other Names Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Cytokeratin-6D, CK-6D, Keratin-6A, K6A, Type-II keratin Kb6, Hom s 5, KRT6A, K6A, KRT6D
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT6A
Synonyms K6A, KRT6D
Function Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
Tissue Location Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath
Research Areas
Citations (0)

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The protein encoded by this gene is a member of thekeratin gene family. The type II cytokeratins consist of basic orneutral proteins which are arranged in pairs of heterotypic keratinchains coexpressed during differentiation of simple and stratifiedepithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes isattributed to successive gene duplication events. The genes areexpressed with family members KRT16 and/or KRT17 in the filiformpapillae of the tongue, the stratified epithelial lining of oralmucosa and esophagus, the outer root sheath of hair follicles, andthe glandular epithelia. This KRT6 gene in particular encodes themost abundant isoform. Mutations in these genes have beenassociated with pachyonychia congenita. The type II cytokeratinsare clustered in a region of chromosome 12q12-q13. [provided byRefSeq].


Dereure, O. Ann Dermatol Venereol 137(5):423-424(2010)Trost, A., et al. Mech. Ageing Dev. 131(5):346-353(2010)Yang, L., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(1):66-68(2010)Millar, E.K., et al. J. Clin. Oncol. 27(28):4701-4708(2009)Bai, Z.L., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 26(5):514-517(2009)

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$ 80.00
Cat# BP16974a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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