|Other Names||Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTC, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain, F9|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.|
|Tissue Location||Synthesized primarily in the liver and secreted in plasma|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes vitamin K-dependent coagulation factorIX that circulates in the blood as an inactive zymogen. This factoris converted to an active form by factor XIa, which excises theactivation peptide and thus generates a heavy chain and a lightchain held together by one or more disulfide bonds. The role ofthis activated factor IX in the blood coagulation cascade is toactivate factor X to its active form through interactions with Ca+2ions, membrane phospholipids, and factor VIII. Alterations of thisgene, including point mutations, insertions and deletions, causefactor IX deficiency, which is a recessive X-linked disorder, alsocalled hemophilia B or Christmas disease.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Yang, L., et al. J. Biol. Chem. 285(37):28488-28495(2010)Kao, C.Y., et al. Thromb. Haemost. 104(2):355-365(2010)Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)Arellano, A.R., et al. J. Thromb. Haemost. 8(5):1132-1134(2010)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.