|Other Names||Zeta-sarcoglycan, Zeta-SG, ZSG1, SGCZ|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. May play a role in the maintenance of striated muscle membrane stability (By similarity).|
|Cellular Location||Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The zeta-sarcoglycan gene measures over 465 kb andlocalizes to 8p22. This protein is part of the sarcoglycan complex,a group of 6 proteins. The sarcoglycans are all N-glycosylatedtransmembrane proteins with a short intra-cellular domain, a singletransmembrane region and a large extra-cellular domain containing acarboxyl-terminal cluster with several conserved cysteine residues.The sarcoglycan complex is part of the dystrophin-associatedglycoprotein complex (DGC), which bridges the inner cytoskeletonand the extra-cellular matrix.
Johnson, A.D., et al. Nat. Genet. 42(7):608-613(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Aurino, S., et al. Acta Myol 27, 90-97 (2008) :Baulac, S., et al. Arch. Neurol. 65(7):943-951(2008)Anastasi, G., et al. J. Histochem. Cytochem. 55(8):831-843(2007)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.