|Other Names||Ras-related protein Rab-28, RAB28|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium basal body. Note=Expressed in the basal body and ciliary rootlet of the photoreceptors.|
|Tissue Location||Isoform S is detected in most tissues investigated: cortex, liver, kidney, skeletal muscle, adipose tissue, testis, urothelium, lung, bone marrow and retinal pigment epithelium (RPE). Isoform L 2 is widely and abundantly expressed all tissues. Isoform 3 is highly expressed in heart, lung, bone marrow, retina, brain, and RPE.|
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This gene encodes a member of the Rab subfamily ofRas-related small GTPases. The encoded protein may be involved inregulating intracellular trafficking. Alternative splicing resultsin multiple transcript variants. Pseudogenes of this gene are foundon chromosomes 9 and X.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Lee, S.H., et al. FEBS Lett. 582(29):4107-4111(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Stenmark, H., et al. Genome Biol. 2 (5), REVIEWS3007 (2001) :Pereira-Leal, J.B., et al. J. Mol. Biol. 301(4):1077-1087(2000)
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