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SEPP1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P49908
Clone Names 100623043
Peptide ID 100623043
Additional Information
Gene ID 6414
Other Names Selenoprotein P, SeP, SEPP1, SELP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPP1
Synonyms SELP
Function Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
Cellular Location Secreted.
Tissue Location Made in the liver and heart and secreted into the plasma. It is also found in the kidney
Research Areas
Citations (0)

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Background

This gene encodes a selenoprotein containing multipleselenocysteine (Sec) residues, which are encoded by the UGA codonthat normally signals translation termination. The 3' UTR ofselenoprotein genes have a common stem-loop structure, the secinsertion sequence (SECIS), which is necessary for the recognitionof UGA as a Sec codon rather than as a stop signal. Thisselenoprotein is an extracellular glycoprotein, and is unusual inthat it contains 10 Sec residues per polypeptide. It is aheparin-binding protein that appears to be associated withendothelial cells, and has been implicated to function as anantioxidant in the extracellular space. Several transcriptvariants, encoding either the same or different isoform, have beenfound for this gene.

References

Sun, W., et al. Br. J. Nutr. 104(9):1283-1287(2010)Roman, M., et al. Transl Res 156(4):242-250(2010)Meplan, C., et al. Carcinogenesis 31(6):1074-1079(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Takemoto, A.S., et al. Ethn Dis 20 (1 SUPPL 1), S1-S925 (2010) :

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$ 80.00
Cat# BP16986c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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