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SIPA1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96FS4
Clone Names 100712021
Peptide ID 100712021
Additional Information
Gene ID 6494
Other Names Signal-induced proliferation-associated protein 1, Sipa-1, GTPase-activating protein Spa-1, p130 SPA-1, SIPA1, SPA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIPA1
Synonyms SPA1
Function GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting it to the putatively inactive GDP-bound state.
Cellular Location Nucleus. Cytoplasm, perinuclear region. Endomembrane system; Peripheral membrane protein. Note=Mostly localized in the perinuclear membraneous region
Tissue Location Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord
Research Areas
Citations (0)

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The product of this gene is a mitogen induced GTPaseactivating protein (GAP). It exhibits a specific GAP activity forRas-related regulatory proteins Rap1 and Rap2, but not for Ran orother small GTPases. This protein may also hamper mitogen-inducedcell cycle progression when abnormally or prematurely expressed. Itis localized to the perinuclear region. Two alternatively splicedvariants encoding the same isoform have been characterized to date.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Brooks, R., et al. Gynecol. Oncol. 116(3):539-543(2010)Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Hsieh, S.M., et al. Breast Cancer Res. 11 (5), R75 (2009) :

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$ 80.00
Cat# BP16989b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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