|Other Names||Bone morphogenetic protein 3, BMP-3, Bone morphogenetic protein 3A, BMP-3A, Osteogenin, BMP3, BMP3A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.|
|Tissue Location||Expressed in adult and fetal cartilage.|
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Provided below are standard protocols that you may find useful for product applications.
BMP3 belongs to the transforming growth factor-beta (TGFB)superfamily. Bone morphogenic protein, also known as osteogenin,induces bone formation.
Stewart, A., et al. J. Cell. Physiol. 223(3):658-666(2010)Chen, X.R., et al. World J. Gastroenterol. 16(11):1409-1413(2010)Wu, D.D., et al. PLoS ONE 5 (6), E10959 (2010) :Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
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