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PAX2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q02962
Clone Names 100507227
Additional Information
Gene ID 5076
Other Names Paired box protein Pax-2, PAX2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAX2
Function Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
Cellular Location Nucleus.
Tissue Location Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system
Research Areas
Citations (0)
citation

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Background

PAX2 encodes paired box gene 2, one of many humanhomologues of the Drosophila melanogaster gene prd. The centralfeature of this transcription factor gene family is the conservedDNA-binding paired box domain. PAX2 is believed to be a target oftranscriptional supression by the tumor supressor gene WT1.Mutations within PAX2 have been shown to result in optic nervecolobomas and renal hypoplasia. Alternative splicing of this generesults in multiple transcript variants.

References

Monte, N.M., et al. Cancer Res. 70(15):6225-6232(2010)Ozcan, A., et al. Arch. Pathol. Lab. Med. 134(8):1121-1129(2010)Quick, C.M., et al. Hum. Pathol. 41(8):1145-1149(2010)Martinovic-Bouriel, J., et al. Am. J. Med. Genet. A 152A (4), 830-835 (2010) :Rabban, J.T., et al. Am. J. Surg. Pathol. 34(2):137-146(2010)

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$ 277.78
Cat# BP17017c
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