|Other Names||Paired box protein Pax-2, PAX2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS.|
|Tissue Location||Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
PAX2 encodes paired box gene 2, one of many humanhomologues of the Drosophila melanogaster gene prd. The centralfeature of this transcription factor gene family is the conservedDNA-binding paired box domain. PAX2 is believed to be a target oftranscriptional supression by the tumor supressor gene WT1.Mutations within PAX2 have been shown to result in optic nervecolobomas and renal hypoplasia. Alternative splicing of this generesults in multiple transcript variants.
Monte, N.M., et al. Cancer Res. 70(15):6225-6232(2010)Ozcan, A., et al. Arch. Pathol. Lab. Med. 134(8):1121-1129(2010)Quick, C.M., et al. Hum. Pathol. 41(8):1145-1149(2010)Martinovic-Bouriel, J., et al. Am. J. Med. Genet. A 152A (4), 830-835 (2010) :Rabban, J.T., et al. Am. J. Surg. Pathol. 34(2):137-146(2010)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.