|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1701b was selected from the C-term region of human HRH4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors.
Lippert, U., et al., J. Invest. Dermatol. 123(1):116-123 (2004).Coge, F., et al., Biochem. Biophys. Res. Commun. 284(2):301-309 (2001).Morse, K.L., et al., J. Pharmacol. Exp. Ther. 296(3):1058-1066 (2001).Zhu, Y., et al., Mol. Pharmacol. 59(3):434-441 (2001).Liu, C., et al., Mol. Pharmacol. 59(3):420-426 (2001).
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