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P2RY13 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BPV8 |
|---|---|
| Clone Names | 100517248 |
| Gene ID | 53829 |
|---|---|
| Other Names | P2Y purinoceptor 13, P2Y13, G-protein coupled receptor 86, G-protein coupled receptor 94, P2RY13, GPR86, GPR94 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | P2RY13 |
|---|---|
| Synonyms | GPR86, GPR94 |
| Function | Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The product of this gene belongs to the family ofG-protein coupled receptors. This family has several receptorsubtypes with different pharmacological selectivity, which overlapsin some cases, for various adenosine and uridine nucleotides. Thisreceptor is activated by ADP.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)Lambert, N.A. Sci Signal 1 (25), RE5 (2008) :Takeda, S., et al. FEBS Lett. 520 (1-3), 97-101 (2002) :
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