|Other Names||Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma, EIF2B3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is one of the subunits ofinitiation factor eIF2B, which catalyzes the exchange of eukaryoticinitiation factor 2-bound GDP for GTP. It has also been found tofunction as a cofactor of hepatitis C virus internal ribosome entrysite-mediated translation. Mutations in this gene have beenassociated with leukodystrophy with vanishing white matter.Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.
Rose, J. Phd, et al. Mol. Med. (2010) In press :Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008)Maletkovic, J., et al. J. Child Neurol. 23(2):205-215(2008)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Mikami, S., et al. Protein Expr. Purif. 46(2):348-357(2006)
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