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KIF20A Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O95235
Clone Names 100528141
Peptide ID 100528141
Additional Information
Gene ID 10112
Other Names Kinesin-like protein KIF20A, GG10_2, Mitotic kinesin-like protein 2, MKlp2, Rab6-interacting kinesin-like protein, Rabkinesin-6, KIF20A, MKLP2, RAB6KIFL
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIF20A
Synonyms MKLP2, RAB6KIFL
Function Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.
Cellular Location Golgi apparatus. Cytoplasm, cytoskeleton, spindle
Research Areas
Citations (0)

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Background

KIF20A interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility (By similarity).

References

Hummer, S., et al. Curr. Biol. 19(7):607-612(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)

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$ 80.00
Cat# BP17031a
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