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HRH4 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H3N8
Clone Names 100617163
Peptide ID 100617163
Additional Information
Gene ID 59340
Other Names Histamine H4 receptor, H4R, HH4R, AXOR35, G-protein coupled receptor 105, GPRv53, Pfi-013, SP9144, HRH4, GPCR105
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HRH4
Synonyms GPCR105
Function The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node
Research Areas
Citations (0)

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Histamine is a ubiquitous messenger molecule released frommast cells, enterochromaffin-like cells, and neurons. Its variousactions are mediated by a family of histamine receptors, which area subset of the G-protein coupled receptor superfamily. This geneencodes a histamine receptor that is predominantly expressed inhaematopoietic cells. The protein is thought to play a role ininflammation and allergy reponses. Multiple transcript variantsencoding different isoforms have been found for this gene.


Yu, B., et al. Br. J. Dermatol. 163(5):935-940(2010)Gschwandtner, M., et al. Allergy 65(7):840-849(2010)Yu, B., et al. Br. J. Dermatol. 162(5):1038-1043(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Smits, R.A., et al. J. Med. Chem. 53(6):2390-2400(2010)

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$ 80.00
Cat# BP17035c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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