|Other Names||Myotubularin-related protein 4, FYVE domain-containing dual specificity protein phosphatase 2, FYVE-DSP2, Zinc finger FYVE domain-containing protein 11, MTMR4, KIAA0647, ZFYVE11|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3).|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=Localized to perinuclear region|
|Tissue Location||Expressed in brain, heart, kidney, spleen, liver, colon, testis, muscle, placenta, thyroid gland, pancreas, ovary, prostate, skin, peripheral blood, and bone marrow|
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Provided below are standard protocols that you may find useful for product applications.
Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3).
Yu, J., et al. J. Biol. Chem. 285(11):8454-8462(2010)Dolley, G., et al. Mol. Genet. Metab. 97(2):149-154(2009)Plant, P.J., et al. Biochem. J. 419(1):57-63(2009)Colland, F., et al. Genome Res. 14(7):1324-1332(2004)Zhao, R., et al. Exp. Cell Res. 265(2):329-338(2001)
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