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HNRPF Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P52597
Clone Names 81028064
Peptide ID 81028064
Additional Information
Gene ID 3185
Other Names Heterogeneous nuclear ribonucleoprotein F, hnRNP F, Nucleolin-like protein mcs94-1, Heterogeneous nuclear ribonucleoprotein F, N-terminally processed, HNRNPF, HNRPF
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1703c was selected from the Center region of human HNRPF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HNRPF
Function Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
Cellular Location Nucleus, nucleoplasm.
Tissue Location Expressed ubiquitously.
Research Areas
Citations (0)

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HNRPF belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences.


Chou,M.Y., Rooke,N. Mol. Cell. Biol. 19 (1), 69-77 (1999)Matunis,M.J., Xing,J. Nucleic Acids Res. 22 (6), 1059-1067 (1994)McDonald,H., Smailus,D. Genomics 13 (2), 344-348 (1992)

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$ 80.00
Cat# BP1703c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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