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DHPS Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P49366
Clone Names 100623267
Peptide ID 100623267
Additional Information
Gene ID 1725
Other Names Deoxyhypusine synthase, DHS, DHPS, DS
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DS
Function Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Research Areas
Citations (0)

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The unusual amino acid hypusine is formedposttranslationally and is only found in a single cellular protein,eukaryotic translation initiation factor 5A. In the first step ofhypusine biosynthesis, deoxyhypusine synthase catalyzes theNAD-dependent transfer of the butylamine moiety of spermidine tothe epsilon-amino group of a specific lysine residue of the EIF5Aprecursor protein to form the intermediate deoxyhypusine residue.This gene consists of nine exons spanning 6.6 kb. Three transcriptvariants have been isolated. However, only transcript variant 1encodes an active protein. The shorter variants may act asmodulating factors of DHPS activity.


Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Alker, A.P., et al. Trop. Med. Int. Health 13(11):1384-1391(2008)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

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$ 80.00
Cat# BP17057a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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