|Other Names||Cytokine receptor-like factor 1, Cytokine-like factor 1, CLF-1, ZcytoR5, CRLF1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development.|
|Tissue Location||Highest levels of expression observed in spleen, thymus, lymph node, appendix, bone marrow, stomach, placenta, heart, thyroid and ovary. Strongly expressed also in fetal lung.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the cytokine type I receptorfamily. The protein forms a secreted complex withcardiotrophin-like cytokine factor 1 and acts on cells expressingciliary neurotrophic factor receptors. The complex can promotesurvival of neuronal cells. Mutations in this gene result inCrisponi syndrome and cold-induced sweating syndrome. [provided byRefSeq].
Tsuritani, K., et al. Calcif. Tissue Int. 86(1):47-57(2010)Crisponi, L., et al. Am. J. Hum. Genet. 80(5):971-981(2007)Dagoneau, N., et al. Am. J. Hum. Genet. 80(5):966-970(2007)Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)Heese, K., et al. J. Cell. Biochem. 91(5):1030-1042(2004)
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