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CRTAP Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75718
Clone Names 110617023
Additional Information
Gene ID 10491
Other Names Cartilage-associated protein, CRTAP, CASP
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRTAP
Synonyms CASP
Function Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Found in articular chondrocytes. Expressed in a variety of tissues
Research Areas
Citations (0)
citation

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Background

The protein encoded by this gene is similar to the chickenand mouse CRTAP genes. The encoded protein is a scaffolding proteinthat may influence the activity of at least one member of thecytohesin/ARNO family in response to specific cellular stimuli.Defects in this gene are associated with osteogenesis imperfecta, aconnective tissue disorder characterized by bone fragility and lowbone mass.

References

Morello, R., et al. Curr Osteoporos Rep 8(2):77-83(2010)Li, G.H., et al. Osteoporos Int 21(6):1009-1020(2010)Fratzl-Zelman, N., et al. Bone 46(3):820-826(2010)Chang, W., et al. Hum. Mol. Genet. 19(2):223-234(2010)Marini, J.C., et al. Cell Tissue Res. 339(1):59-70(2010)

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$ 277.78
Cat# BP17060a
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