|Other Names||Cyclin-K, CCNK, CPR4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).|
|Tissue Location||Ubiquitously expressed. Highest levels in testis.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of thetranscription cyclin family. These cyclins may regulatetranscription through their association with and activation ofcyclin-dependent kinases (CDK) that phosphorylate the C-terminaldomain (CTD) of the large subunit of RNA polymerase II. This geneproduct may play a dual role in regulating CDK and RNA polymeraseII activities.
Marsaud, V., et al. Mol. Cancer 9, 103 (2010) :Baek, K., et al. J. Mol. Biol. 366(2):563-573(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Lim, J., et al. Cell 125(4):801-814(2006)
If you have any additional inquiries please email technical services at email@example.com.