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SERINC3 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q13530
Clone Names 110617080
Peptide ID 110617080
Additional Information
Gene ID 10955
Other Names Serine incorporator 3, Tumor differentially expressed protein 1, SERINC3, DIFF33, TDE1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERINC3
Synonyms DIFF33, TDE1 {ECO:0000303|PubMed:1055979
Function Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734).
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q86VE9}; Multi-pass membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9QZI9}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9QZI9}
Tissue Location Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.
Research Areas
Citations (0)

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Background

SERINC3 may be involved in cellular transformation.

References

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Bossolasco, M., et al. Oncogene 25(33):4549-4558(2006)Deloukas, P., et al. Nature 414(6866):865-871(2001)Bossolasco, M., et al. Mol. Carcinog. 26(3):189-200(1999)Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995) :

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$ 80.00
Cat# BP17065b
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