|Other Names||Centrosomal protein of 57 kDa, Cep57, FGF2-interacting protein, Testis-specific protein 57, Translokin, CEP57, KIAA0092, TSP57|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring- like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.|
|Cellular Location||Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome|
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Provided below are standard protocols that you may find useful for product applications.
Translokin binds basic fibroblast growth factor (FGF2; MIM134920) and mediates its nuclear translocation and mitogenicactivity (Bossard et al., 2003 [PubMed 12717444]).[supplied byOMIM].
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Petretti, C., et al. EMBO Rep. 7(4):418-424(2006)Kim, Y.S., et al. Biol. Reprod. 70(1):106-113(2004)Andersen, J.S., et al. Nature 426(6966):570-574(2003)
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