|Other Names||Peptidyl-prolyl cis-trans isomerase-like 3, PPIase, Cyclophilin J, CyPJ, Cyclophilin-like protein PPIL3, Rotamase PPIL3, PPIL3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.|
|Tissue Location||Ubiquitous. Detected at low levels.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the cyclophilin family.Cyclophilins catalyze the cis-trans isomerization of peptidylprolylimide bonds in oligopeptides. They have been proposed to act eitheras catalysts or as molecular chaperones in protein-folding events.Alternative splicing results in multiple transcript variants.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Huo, D.H., et al. Biochem. Biophys. Res. Commun. 372(1):14-18(2008)Qi, Z.Y., et al. Chin. Med. J. 118(10):799-805(2005)Hillier, L.W., et al. Nature 434(7034):724-731(2005)Huang, L.L., et al. Acta Crystallogr. D Biol. Crystallogr. 61 (PT 3), 316-321 (2005) :
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