|Other Names||Osteoclast-stimulating factor 1, OSTF1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.|
|Tissue Location||Ubiquitously expressed. Present in osteoclasts (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Osteoclast-stimulating factor-1 is an intracellularprotein produced by osteoclasts that indirectly induces osteoclastformation and bone resorption (Reddy et al., 1998 [PubMed10092216]).
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Tong, S., et al. Proteins 75(1):245-251(2009)Voss, M., et al. BMC Immunol. 10, 53 (2009) :Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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