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Bmp10 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O95393
Clone Names 2080411
Peptide ID 2080411
Additional Information
Gene ID 27302
Other Names Bone morphogenetic protein 10, BMP-10, BMP10
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1710a was selected from the N-term region of human Bmp10 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMP10
Function Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Cellular Location Secreted.
Tissue Location Detected in mammary epithelia (at protein level).
Research Areas
Citations (0)

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BMP10 is a member of the TGF-beta family of growth factors. Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart. In human, this protein may signal through receptor serine/threonine kinases.


Neuhaus, H., et al., Mech. Dev. 80(2):181-184 (1999).

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$ 80.00
Cat# BP1710a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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