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Bmp15 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O95972 |
|---|---|
| Other Accession | NP_005439 |
| Clone Names | 2080412 |
| Gene ID | 9210 |
|---|---|
| Other Names | Bone morphogenetic protein 15, BMP-15, Growth/differentiation factor 9B, GDF-9B, BMP15, GDF9B |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1711a was selected from the N-term region of human Bmp15 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BMP15 |
|---|---|
| Synonyms | GDF9B |
| Function | May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Bmp15 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9.
References
Liao, W.X., et al., J. Biol. Chem. 278(6):3713-3719 (2003).Moore, R.K., et al., J. Biol. Chem. 278(1):304-310 (2003).Galloway, S.M., et al., Nat. Genet. 25(3):279-283 (2000).Aaltonen, J., et al., J. Clin. Endocrinol. Metab. 84(8):2744-2750 (1999).Dube, J.L., et al., Mol. Endocrinol. 12(12):1809-1817 (1998).
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