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GCNT1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q02742
Clone Names 100617100
Peptide ID 100617100
Additional Information
Gene ID 2650
Other Names Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Core 2-branching enzyme, Core2-GlcNAc-transferase, C2GNT, Core 2 GNT, GCNT1, NACGT2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GCNT1
Synonyms NACGT2
Function Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein. Note=Also detected in the trans-Golgi network
Tissue Location Highly expressed in activated T-lymphocytes and myeloid cells
Research Areas
Citations (0)

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This gene is a member of thebeta-1,6-N-acetylglucosaminyltransferase gene family. It isessential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAcstructures and the core 2 O-glycan branch. The gene coding thisenzyme was originally mapped to 9q21, but was later localized to9q13. Multiple alternatively spliced variants, encoding the sameprotein, have been identified.


Hatakeyama, S., et al. Int. J. Cancer 127(5):1052-1059(2010)Brockhausen, I., et al. Biochim. Biophys. Acta 1790(10):1244-1257(2009)St Hill, C.A., et al. BMC Cancer 9, 79 (2009) :Nagaraj, S., et al. Pancreas 37(3):321-327(2008)Julien, S., et al. J. Immunol. 179(9):5701-5710(2007)

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$ 80.00
Cat# BP17151c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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