|Other Names||Protein Jade-3, Jade family PHD finger protein 3, PHD finger protein 16, JADE3, KIAA0215, PHF16|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.|
|Tissue Location||Ubiquitously expressed, with highest levels in placenta and uterus.|
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Provided below are standard protocols that you may find useful for product applications.
This gene is part of a gene cluster on chromosome Xp11.23.The encoded protein contains a zinc finger motif often found intranscriptional regulators, however, its exact function is notknown. Alternative splicing results in multiple transcript variantsencoding the same protein.
Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Doyon, Y., et al. Mol. Cell 21(1):51-64(2006)Ross, M.T., et al. Nature 434(7031):325-337(2005)Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
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