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BCL7B Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BQE9
Clone Names 110617298
Additional Information
Gene ID 9275
Other Names B-cell CLL/lymphoma 7 protein family member B, Hom s 3, BCL7B
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL7B
Function Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1 (PubMed:25569233). Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation (PubMed:25569233). May play a role in lung tumor development or progression (By similarity).
Tissue Location Ubiquitous.
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the BCL7 family includingBCL7A, BCL7B and BCL7C proteins. This member is BCL7B, whichcontains a region that is highly similar to the N-terminal segmentof BCL7A or BCL7C proteins. The BCL7A protein is encoded by thegene known to be directly involved in a three-way genetranslocation in a Burkitt lymphoma cell line. This gene is locatedat a chromosomal region commonly deleted in Williams syndrome. Thisgene is highly conserved from C. elegans to human. Multiplealternatively spliced transcript variants have been found for thisgene.

References

Fontaine-Bisson, B., et al. Diabetologia 53(10):2155-2162(2010)Kathiresan, S., et al. Nat. Genet. 40(2):189-197(2008)Willer, C.J., et al. Nat. Genet. 40(2):161-169(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)Jadayel, D.M., et al. Gene 224 (1-2), 35-44 (1998) :

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$ 277.78
Cat# BP17168b
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