|Other Names||Ly-6/neurotoxin-like protein 1, Secreted Ly-6/uPAR domain-containing protein 2, Secreted Ly-6/uPAR-related protein 2, SLURP-2, LYNX1, SLURP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the Ly-6/neurotoxin genefamily, a group of lymphocyte antigens that attach to the cellsurface by a glycosylphosphatidylinositol anchor and have a uniquestructure showing conserved 8-10 cysteine residues with acharacteristic spacing pattern. Functional analysis indicates thatthis protein is not a ligand or neurotransmitter but has thecapacity to enhance nicotinic acetylcholine receptor function inthe presence of acetylcholine. This gene may also play a role inthe pathogenesis of psoriasis vulgaris. Alternatively splicedvariants encoding different isoforms have been identified.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Choi, S.H., et al. Int. J. Oncol. 35(3):601-607(2009)Song, P., et al. Cancer Res. 68(12):4693-4700(2008)Arredondo, J., et al. Biochem. Pharmacol. 74(8):1315-1319(2007)Lee, J.W., et al. Oncol. Rep. 16(6):1211-1214(2006)
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