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NKX3-1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99801
Clone Names 100427213
Peptide ID 100427213
Additional Information
Gene ID 4824
Other Names Homeobox protein Nkx-31, Homeobox protein NK-3 homolog A, NKX3-1, NKX31, NKX3A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKX3-1
Synonyms NKX3.1, NKX3A
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:11137288}
Tissue Location Highly expressed in the prostate and, at a lower level, in the testis.
Research Areas
Citations (0)

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The homeodomain-containing transcription factor NKX3-1 isa putative prostate tumor suppressor that is expressed in a largelyprostate-specific and androgen-regulated manner. Loss of NKX3-1protein expression is a common finding in human prostate carcinomasand prostatic intraepithelial neoplasia.


Kim, S.T., et al. Prostate 70(16):1729-1738(2010)Takata, R., et al. Nat. Genet. 42(9):751-754(2010)Gurel, B., et al. Am. J. Surg. Pathol. 34(8):1097-1105(2010)Bowen, C., et al. Cancer Res. 70(8):3089-3097(2010)Kunderfranco, P., et al. PLoS ONE 5 (5), E10547 (2010) :

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$ 80.00
Cat# BP17186b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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