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ORAI3 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BRQ5
Clone Names 100603200
Additional Information
Gene ID 93129
Other Names Protein orai-3, Transmembrane protein 142C, ORAI3, TMEM142C
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ORAI3
Synonyms TMEM142C
Function Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in both naive and effector T helper cells with higher levels in effector cells.
Research Areas
Citations (0)
citation

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Background

Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import (By similarity).

References

Motiani, R.K., et al. J. Biol. Chem. 285(25):19173-19183(2010)Bogeski, I., et al. Sci Signal 3 (115), RA24 (2010) :Schindl, R., et al. Proc. Natl. Acad. Sci. U.S.A. 106(46):19623-19628(2009)Lee, K.P., et al. Proc. Natl. Acad. Sci. U.S.A. 106(34):14687-14692(2009)Frischauf, I., et al. J. Biol. Chem. 284(32):21696-21706(2009)

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$ 277.78
Cat# BP17188a
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