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Bmp7 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P18075
Other Accession NP_001710
Clone Names 2080409
Peptide ID 2080409
Additional Information
Gene ID 655
Other Names Bone morphogenetic protein 7, BMP-7, Osteogenic protein 1, OP-1, Eptotermin alfa, BMP7, OP1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1718a was selected from the N-term region of human Bmp7 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMP7
Synonyms OP1
Function Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Cellular Location Secreted.
Tissue Location Expressed in the kidney and bladder. Lower levels seen in the brain
Research Areas
Citations (0)

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The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.


Merrihew, C., et al., J. Orthop. Res. 21(5):899-907 (2003).Greenwald, J., et al., Mol. Cell 11(3):605-617 (2003).Maric, I., et al., J. Cell. Physiol. 196(2):258-264 (2003).Im, H.J., et al., J. Biol. Chem. 278(28):25386-25394 (2003).Lee, M.J., et al., J. Immunol. 170(5):2557-2563 (2003).

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$ 80.00
Cat# BP1718a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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