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NOX1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y5S8
Clone Names 100617236
Additional Information
Gene ID 27035
Other Names NADPH oxidase 1, NOX-1, 1---, Mitogenic oxidase 1, MOX-1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NOH-1, NOX1, MOX1, NOH1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOX1
Synonyms MOX1, NOH1
Function NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor.
Cellular Location Cell projection, invadopodium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location [Isoform NOH-1L]: Detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes
Research Areas
Citations (0)
citation

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Background

Voltage-gated proton (hydrogen) channels play an importantrole in cellular defense against acidic stress. They are uniqueamong ion channels with respect to their extremely highselectivity, marked temperature dependence, and unitaryconductance, which is 3 orders of magnitude lower than that of mostother ion channels. NOX1 is a homolog of the catalytic subunit ofthe superoxide-generating NADPH oxidase of phagocytes, gp91phox.Two transcript variants encoding different isoforms have been foundfor this gene.

References

Sancho, P., et al. J. Biol. Chem. 285(32):24815-24824(2010)van Bruggen, R., et al. Blood 115(26):5398-5400(2010)Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)Malec, V., et al. Free Radic. Biol. Med. 48(12):1626-1635(2010)Manea, A., et al. Biochem. Biophys. Res. Commun. 396(4):901-907(2010)

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$ 277.78
Cat# BP17191c
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