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NOX1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9Y5S8
Clone Names 100617236
Peptide ID 100617236
Additional Information
Gene ID 27035
Other Names NADPH oxidase 1, NOX-1, 1---, Mitogenic oxidase 1, MOX-1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NOH-1, NOX1, MOX1, NOH1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOX1
Synonyms MOX1, NOH1
Function NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.
Cellular Location Cell projection, invadopodium membrane; Multi-pass membrane protein
Tissue Location NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH- 1S is detected only in colon and colon carcinoma cells
Research Areas
Citations (0)

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Voltage-gated proton (hydrogen) channels play an importantrole in cellular defense against acidic stress. They are uniqueamong ion channels with respect to their extremely highselectivity, marked temperature dependence, and unitaryconductance, which is 3 orders of magnitude lower than that of mostother ion channels. NOX1 is a homolog of the catalytic subunit ofthe superoxide-generating NADPH oxidase of phagocytes, gp91phox.Two transcript variants encoding different isoforms have been foundfor this gene.


Sancho, P., et al. J. Biol. Chem. 285(32):24815-24824(2010)van Bruggen, R., et al. Blood 115(26):5398-5400(2010)Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)Malec, V., et al. Free Radic. Biol. Med. 48(12):1626-1635(2010)Manea, A., et al. Biochem. Biophys. Res. Commun. 396(4):901-907(2010)

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$ 80.00
Cat# BP17191c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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