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PRKAR1B Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P31321
Clone Names 100507175
Additional Information
Gene ID 5575
Other Names cAMP-dependent protein kinase type I-beta regulatory subunit, PRKAR1B
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRKAR1B
Function Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Cellular Location Cell membrane.
Tissue Location Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible
Research Areas
Citations (0)
citation

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Background

Cyclic AMP-dependent protein kinase A (PKA) is anessential enzyme in the signaling pathway of the second messengercAMP. Through phosphorylation of target proteins, PKA controls manybiochemical events in the cell including regulation of metabolism,ion transport, and gene transcription. The PKA holoenzyme iscomposed of 2 regulatory and 2 catalytic subunits and dissociatesfrom the regulatory subunits upon binding of cAMP.[supplied byOMIM].

References

Silva, L.K., et al. Eur. J. Hum. Genet. (2010) In press :Liu, Y.J., et al. Obesity (Silver Spring) (2010) In press :Zhan, X., et al. Anal. Biochem. 354(2):279-289(2006)Gullingsrud, J., et al. Structure 14(1):141-149(2006)Zhang, L., et al. Mol. Cell. Biol. 24(5):2169-2180(2004)

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$ 277.78
Cat# BP17198a
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