|Other Names||Sal-like protein 1, Spalt-like transcription factor 1, Zinc finger protein 794, Zinc finger protein SALL1, Zinc finger protein Spalt-1, HSal1, Sal-1, SALL1, SAL1, ZNF794|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor involved in organogenesis.|
|Tissue Location||Highest levels in kidney. Lower levels in adult brain (enriched in corpus callosum, lower expression in substantia nigra) and liver|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a zinc fingertranscriptional repressor and may be part of the NuRD histonedeacetylase complex (HDAC). Defects in this gene are a cause ofTownes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome(BOR). Two transcript variants encoding different isoforms havebeen found for this gene.
Yamamoto, C., et al. Hypertens. Res. 33(2):143-148(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Ramdas, W.D., et al. PLoS Genet. 6 (6), E1000978 (2010) :Lu, J., et al. PLoS ONE 4 (5), E5577 (2009) :de Celis, J.F., et al. Int. J. Dev. Biol. 53 (8-10), 1385-1398 (2009) :
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