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RBMS1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P29558
Clone Names 100517177
Additional Information
Gene ID 5937
Other Names RNA-binding motif, single-stranded-interacting protein 1, Single-stranded DNA-binding protein MSSP-1, Suppressor of CDC2 with RNA-binding motif 2, RBMS1, C2orf12, MSSP, MSSP1, SCR2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RBMS1
Synonyms C2orf12, MSSP, MSSP1, SCR2
Function Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.
Cellular Location Nucleus.
Tissue Location Highest amounts are found in placenta, lung and heart
Research Areas
Citations (0)
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Background

This gene encodes a member of a small family of proteinswhich bind single stranded DNA/RNA. These proteins arecharacterized by the presence of two sets of ribonucleoproteinconsensus sequence (RNP-CS) that contain conserved motifs, RNP1 andRNP2, originally described in RNA binding proteins, and requiredfor DNA binding. These proteins have been implicated in suchdiverse functions as DNA replication, gene transcription, cellcycle progression and apoptosis. Several transcript variants,resulting from alternative splicing and encoding differentisoforms, have been described. A pseudogene for this locus is foundon chromosome 12.

References

Qi, L., et al. Hum. Mol. Genet. 19(13):2706-2715(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Landers, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(22):9004-9009(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 277.78
Cat# BP17208c
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